Temple University 3 credits QARA
This course considers the interrelationship of the physicochemical properties of the drug, the dosage form, and the route of administration on the rate and extent of systemic drug absorption. Drug absorption mechanisms, physiological and GIT constraints on dosage form transit and bioavailbility, effect of formulation parameters, dissolution methodologies, in-vitro/in-vivo correlation of drug product performance as well as PAC, ICH and FDA guidelines on development and approval process will be covered. Formulation strategies for optimum therapeutic outcome via application of pharmaceutical sciences to the design of drug delivery systems is provided.
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