Temple University 3 credits PS
The emphasis of this course is to form a bridge between the concepts of physical pharmacy and the application of these principles to drug development. Students will understand basic aspects of oral absorption, high performance liquid chromatography (HPLC), physical properties of solutions, ionic equilibrium, buffers and isotonic solutions, solubility and partition phenomena, complexation and protein binding, reaction kinetics, mass transport, dissolution phenomena, salt selection and polymorphism. Pharmaceutical applications grounded on basic principles will be discussed as well. Students will be expected to be able to apply the basic concepts from this course to typical formulation and stability issues of pharmaceutical dosage forms.
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