University of Arizona 5 credits Pharmacy Practice & Science
The goal of this course is to provide the foundational principles and processes of drug absorption, distribution, metabolism, and elimination, and skills necessary to interpret and apply pharmacokinetic principles in the design and optimization of drug therapy. Students will develop an understanding of basic pharmacokinetic terms and principles, learn how to analyze data, and evaluate the literature with regard to drug absorption and disposition. Through application of mathematical models of plasma concentration versus time curves following drug administration, pharmacokinetic parameters can be estimated to design and predict optimal drug dosing regimens for individual patients. Emphasis is placed on applying population average pharmacokinetic parameters and measured drug concentrations to determine dosage regimens for individual patients. Factors that lead to variability in pharmacokinetic parameters between and within individuals will also be stressed. Students will evaluate the impact of variability on the development of dosage regimens utilizing patient cases.
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