University at Buffalo 2 credits Pharmacy
PHM557 is a 2-credit-hour course designed for Doctor of Pharmacy students, MS in Clinical and Translational Therapeutics graduate and other professional students in related disciplines. It offers an introductory overview of the principles and methods of genomics and bioinformatics, emphasizing the integration of modern sequencing technologies with computational analysis. Using bacterial genomics as the primary model system, students will gain hands-on experience in genome assembly, annotation, comparative genomics, and key bioinformatics workflows. The course also includes a wet lab component covering essential molecular biology techniques such as DNA isolation, PCR, Sanger sequencing, next-generation sequencing (NGS) library preparation, and CRISPRC as-mediated gene knockout. These laboratory exercises reinforce computational training and illustrate the complete workflow from data generation to biological insight.
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