Temple University 3 credits NSCI
In the broadest sense, the term epigenetics refers to the study of environmental influences on gene expression. These processes encompass a multitude of mechanisms by which DNA is regulated, all of which are independent of DNA mutation. Epigenetic modifications are highly dynamic and respond quickly to environmental changes, such as diet or stress. Epigenetic marks represent concrete mechanisms for the long-held idea that biology and behavior are shaped by complex interactions between genetic and environmental factors. Some of these epigenetic marks are passed on to future generations via the germline and influence neuroprogramming in the next generation offspring. In the brain, where most neurons are post-mitotic, epigenetic processes play a critical role in regulating gene expression and synaptic plasticity, which are pivotal events for the regulation of behavior.
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