University of Delaware 3 credits MMSC
This course explores the molecular basis and diagnosis of inherited diseases, covering single-gene and complex disorders, inheritance patterns, and allele frequencies. Topics include chromosomal structures, disease-causing mutations, and detection methods. Gene regulation principles, including epigenetic mechanisms, abnormal regulation in Mendelian disorders, and DNA testing applications in transplantation, paternity, and forensics, are addressed. Ethical considerations in genetic testing and DNA-based therapies will also be discussed. Prerequisite: BISC 208 and BISC 218 and CHEM 104 and CHEM 134 .
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