University at Buffalo 3 credits Medicinal Chemistry
This course focuses on the fundamental aspects and current methodologies involved in the drug discovery process. The fundamental aspects include the physical, chemical and pharmaceutical properties of drugs. The methodologies include lead discovery strategies, statistically based 2D and 3D QSAR optimization methods, structure-based and mechanism-based design methods, and combinatorial techniques. Application to the chemotherapy of cancer, viral and microbial diseases will be examined.
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