Johns Hopkins University 3 credits Applied Biomedical Engineering
Neuroimaging provides a fascinating and versatile window into how the brain works. This course introduces students to both structural and functional Magnetic Resonance Imaging (fMRI) techniques used to investigate the neural basis of cognition. It is well-suited for beginners who are simply curious, as well as for more advanced students eager to deepen their understanding of how the mind can be studied through brain imaging. The course will be delivered asynchronously and will include hands-on, computer-based lab exercises. Students will gain practical experience working with MRI and fMRI data, including how to open and navigate brain imaging files, draw lesions in damaged brains, run basic functional MRI and connectivity analyses, and generate their own neuroimaging meta-analysis. In addition to developing technical skills, students will learn to explain key turning points in the history of fMRI research, such as the discovery and validation of the BOLD response, shifts in experimental design (e.g., block versus event-related paradigms), the emergence of connectivity analyses, and the development of more advanced approaches like fMRI adaptation and pattern-based analysis. Finally, students will critically examine major challenges in the field, including common pitfalls in interpreting fMRI results, the reproducibility crisis in neuroimaging research, and current ethical issues related to the use of fMRI.
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