Pennsylvania State University 3 credits BME
Engineering and biological principles as applied to pharmaceutical transport and designing drug carriers. BME 433 Drug Delivery (3) The success of drug delivery depends on not only the understanding of chemical synthesis, polymer sciences, and cell biology, but also the fundamental understanding of drug transport that is affected by both drug's properties and physiological barriers, which are very critical but often overlooked in the design of drug delivery systems. Therefore, this course covers two main issues: 1) physiological barriers and drug transport; 2) design and characterization of drug delivery systems. The first section of this course introduces transport mechanisms of drug delivery at the levels of cell, tissue and wholebody from the engineering viewpoint. The second section describes the rational design of various drug delivery systems and emphasizes nanomedicines. Case studies of cancer therapy/tissue engineering are described to compare, contrast and analyze current drug delivery systems.
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