Temple University 3 credits BIOE
Mechanobiology is an emerging interdisciplinary field that focuses on the role of mechanical cues in governing cellular behavior. This course will address how a cell utilizes its adhesions to neighboring cells and to the surrounding extracellular matrix to sense external forces and furthermore, how these forces are transduced within the cell to alter cellular behavior and regulate tissue architecture. This course will also discuss how the extracellular matrix influences cellular behavior during development, health, and disease. Additionally, this course will also discuss the various tools and techniques developed to probe cytoskeletal structures, molecular motors, plasma membranes, cellular adhesion structures, and matrix proteins that pushed the field of mechanobiology forward. This course will culminate in integrating all new foundational knowledge in mechanobiology to propose new studies manipulating molecular, cellular, or tissue-level behavior for applications in diverse fields such as regenerative engineering, wound healing, or cancer diagnostics.
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